CIRQUA aims to improve nature-based solutions (NBS), focusing on constructed wetlands (CWs) for wastewater treatment and water recovery in rural areas. These solutions are widely-used, safe, decentralized, easy to operate and environmentally-friendly. They can help meet the strict legislative EU requirements, increasing water efficiency and conserving water resources in the Mediterranean region, advancing resilience in view of Climate Change challenges. They can also valorize non-conventional nutrient resources for precision irrigation and fertilization, which is a pillar of sustainable agriculture. CIRQUA will upgrade CWs using technological achievements, such as innovative nanostructured filters and photocatalytic modules, cultivation of N₂-fixing legumes, sensors and automation in operation, precision irrigation principles and integration of advanced artificial intelligence (AI) tools. These innovations will aid improve effluent quality, allowing the treated water and CW biomass to be used for irrigation and fertilization purposes, thus promoting circular economy at local scale.